Capsaicin Design Platform
Design your cultivar.
Export the construct.
The Capsaicin Design Platform gives you the same tools we used to design 1,000 cultivars — FBA simulation, CRISPR guide generation, ESM2 protein scanning, and direct-to-synthesis export.
Free to start · No credit card required · DESIGNER tier on first login
How it works
01
Pick your target SHU
Choose a heat level anywhere from 0.9M to 2.9M SHU. The designer shows you which organisms and tier can reach it.
02
Select your host organism
Start with Capsicum chinense or go cross-species — tomato, strawberry, cannabis. 65 organisms in the catalog.
03
Run the flux model
The FBA simulator identifies the rate-limiting step for your specific organism and computes the theoretical capsaicinoid ceiling.
04
Export your construct
Download synthesis-ready files for IDT or Twist — complete with CRISPR guides, promoters, codon-optimized sequences, and GenBank annotations.
What's in the platform
Every tool is wired to the same backend that produced the 1,000-cultivar catalog. Real engines, not demos.
Blend calculator
Set a target SHU and the system designs the exact 5-capsaicinoid ratio — including burn profile (onset, peak, duration).
CRISPR guide designer
Generate Cas9 guide RNAs for any locus in the target organism. Ranked by specificity, off-target risk, and predicted editing efficiency.
ESM2 protein scanner
Scan every single-amino-acid substitution in capsaicin synthase (Pun1) and rank by predicted stability and activity.
Codon optimizer
One click: rewrite any Capsicum coding sequence to the codon usage of your chosen host organism.
Primer designer
Design amplification and sequencing primers around any edit site. Tm-matched pairs, no manual calculation.
Export to lab
GenBank / FASTA / SBOL / IDT OligoAnalyzer / Twist formats. Copy-paste into your order form.
Or start from the catalog
1,000 cultivars ready to license
Don't want to design from scratch? Browse 1,000 cultivars spanning 0.9M to 2.9M SHU across 65 species. Every product ships as a complete synthesis-ready design package.
Pepper
10 cultivars
Tier 1
Solanaceae
Tier 2
Nightshades
Tier 3
Cross-family
Tier 4
Frontier
Tier 5
Reserved
Ready to start designing?
DESIGNER tier is free to try. No credit card. Start with the blend calculator or browse the full catalog.
Get started free