Early morning light falling across a nursery bench of young pepper plants

Platform

How it works

Four decisions and a browser tab. Choose a host organism, name a heat target, let the platform compute a design, and review what it produced before anything leaves the building.

65

host organisms

1,000

reference constructs

100 โ€“ 16M

SHU range

6

heat tiers

01

What you bring to it

The platform asks for four things, and none of them require you to have written any code. A host organism, chosen from the 65 the catalog covers. A heat target, placed anywhere on a ladder that runs from 100 SHU to 16,000,000 SHU. A burn profile that says how the heat should arrive and how long it should linger. And a tissue, because a target that makes sense in fruit rarely makes sense in a leaf.

Those four selections live in a short form on the project screen. Submit them and the platform does something useful before any computation starts: it shows you the nearest entries from the catalog, so you can see at a glance whether your target sits inside well-mapped territory or out at a sparse edge. SS-0421 and its neighbours are not decoration. They are the evidence that tells you how much to trust what comes next.

02

The screens you work in

Screen

Dashboard

Every project you own or share, with its status, its last run, and its remaining credit balance. Jobs that are still queued show their position; jobs that finished overnight are waiting with a result badge.

Screen

Catalog browser

All 1,000 reference constructs, filterable by organism, by series across the 70 the catalog defines, and by tier from Pepper up through Tier 5. Open any entry to see what it targeted and what it measured.

Screen

Designer

The working surface. Pathway on the left as an Escher map, candidate enzymes in the middle, the construct taking shape on the right. Every panel is editable, and every edit is recorded as a revision.

Screen

Run console

What is computing, what it costs, and how far along it is. CPU engines return in the page. GPU work shows a queue position and a class, and you can keep working while it runs.

Screen

Compare

Two or more design revisions side by side, with predicted heat, composition and construct size aligned row for row. Measured values stay visually distinct from predicted ones throughout.

Screen

Export drawer

The handoff. Choose GenBank, FASTA or SBOL, add the order sheets and the manifest, and download a package that names every engine version that touched the design.

03

A first session, start to finish

Step 1
Create project, choose host and tissue
Step 2
Set heat target and burn profile
Step 3
Run flux analysis โ€” CPU, returns in-page
Step 4
Scan enzyme variants โ€” GPU, queued
Step 5
Review shortlist, pick candidates
Step 6
Assemble construct, validate, export
Elapsed
An afternoon, most of it reading

Notice how much of that is reading rather than waiting. The flux step runs on CPU and comes back while you are still looking at the map, and it answers the question that matters earliest: can this host fund this target at all? A ceiling below your number is not a failure of the software. It is a season of greenhouse space you did not spend.

Only the variant scan leaves the browser for a GPU worker, and it queues rather than blocking you. Start it, go read the catalog neighbours, come back to a scored shortlist. Nothing about the session demands that you sit and watch a progress bar.

04

Review, then hand it off

A finished design is reviewable by someone who was not in the room. The project record carries the model and its assumptions, the scored variants with the reasoning behind the shortlist, the edit plan with its off-target evidence, the assembled construct, and a dated manifest. Collaborators see what was decided and on what basis, which is the difference between a result and a claim.

Cost follows the same logic as the screens. Flux modelling, codon work, primer design, annotation, assembly and export are CPU engines and run free, however many times you revise. GPU engines draw on prepaid credits โ€” $25 buys 250 credits, one credit covers roughly one Standard job, with Performance and Max classes available when a structure earns the extra compute. Most first projects never leave the free tier at all.

Ready to run it

Try this in the Splice Platform.

CPU engines are free to run. GPU engines run on prepaid credits.

Open the dashboard โ†’

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