IFI-S · Nectar Tier

Specimen SS-F-SWT-084 // SWEET · IFI-S

Nectar Tier I-BL-B

Stevia rebaudiana

Stevia

Tier INectar Tier

Target Trait

2.88×

fold-change

TRPM5 downstream sweet signal amplification fold-change

Technical Specifications

Genomic Edits

3

GC Content

46.9%

Construct Length

4,580 bp

Promoter System

CaMV 35S / Ubiquitin

Expression System

Biolistic transformation

Host Strain

Particle Gun

Receptor Target

TAS1R2/TAS1R3

IFI Score

288

Pathway Edits

  • TRPM5 channel expression upregulation in gustatory epithelium cassette
  • TAS1R2/TAS1R3 heterodimer membrane trafficking optimization sequence
  • Phospholipase C beta-2 activity enhancement cassette

Key Interventions

TRPM5 gating kinetics optimization via S4-S5 linker modificationReceptor recycling pathway acceleration through endosomal sorting elementInositol phosphate cascade amplification via ITPR3 upregulation

IFI Subscale Profile

IFI Profile

IFI-S
288
IFI-U
—
IFI-B
—
IFI-K
—
IFI-C
—
IFI-P
—
IFI-A
—
IFI-F
—

Use Case

Enhanced performance plant-derived sweetener potency multiplier for functional beverages with amplified TAS1R2/TAS1R3 receptor activation for premium-tier applications

License

$99 · Tier I License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

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