Glycan Peak I-AG-B

Capsicum chinense

Pepper

Tier IGlycan Peak

Target Trait

2.07×

fold-change

N-glycoprotein sweetness signal transduction amplification

Technical Specifications

Genomic Edits

GC Content

44.4%

Construct Length

4,580 bp

Promoter System

Tissue-specific 2A11

Expression System

Agrobacterium-mediated T-DNA

Host Strain

EHA105

Receptor Target

TAS1R2/TAS1R3

IFI Score

207

Pathway Edits

TAS1R2 N-glycosylation site Asn-44 remodeling for glycan shielding
UGT76G1 steviol glycoside biosynthesis pathway upregulation cassette
PLCβ2 signaling cascade efficiency optimization via PDZ domain edit

Key Interventions

Glycan shield engineering at VFT domain dimer interfaceReceptor dimerization stability enhancement via disulfide lock insertionIP3-mediated Ca2+ release amplification in taste receptor cells

IFI Subscale Profile

IFI Profile

IFI-S

207

IFI-U

—

IFI-B

—

IFI-K

—

IFI-C

—

IFI-P

—

IFI-A

—

IFI-F

—

Use Case

Enhanced performance stevioside bioavailability enhancement platform with amplified TAS1R2/TAS1R3 receptor activation for premium-tier applications

License

$99 · Tier I License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

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