IFI-K · Kokumi Peak

Specimen SS-F-KOK-170 // KOKUMI · IFI-K

Kokumi Peak II-AG-B

Allium sativum

Garlic

Tier IIKokumi Peak

Target Trait

4.31×

fold-change

Peak kokumi intensity fold-change at sensory panel assessment

Technical Specifications

Genomic Edits

9

GC Content

54.7%

Construct Length

2,840 bp

Promoter System

Tissue-specific 2A11

Expression System

Agrobacterium-mediated T-DNA

Host Strain

EHA105

Receptor Target

CaSR (calcium-sensing receptor)

IFI Score

646.5

Pathway Edits

  • CaSR agonist residence-time extension edit
  • Orthosteric binding site affinity maturation
  • Calcilytic sensitivity removal
  • GRK5/6 expression silencing
  • Ubiquitin ligase Nedd4-2 suppression
  • Receptor recycling endosome acceleration
  • Palmitoylation site optimization
  • GPCR-associated sorting protein silencing

Key Interventions

extended agonist dwell-time at CaSRreceptor recycling and resensitization acceleration

IFI Subscale Profile

IFI Profile

IFI-S
—
IFI-U
—
IFI-B
—
IFI-K
646.5
IFI-C
—
IFI-P
—
IFI-A
—
IFI-F
—

Use Case

Artisan fermented garlic concentrate base

License

$149 · Tier II License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

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