IFI-K · CaSR Enhance

Specimen SS-F-KOK-097 // KOKUMI · IFI-K

CaSR Enhance III-AG-A

Capsicum annuum

Pepper

Tier IIICaSR Enhance

Target Trait

3.25×

fold-change

CaSR receptor activation fold-change over wild-type

Technical Specifications

Genomic Edits

7

GC Content

50.6%

Construct Length

2,500 bp

Promoter System

Tissue-specific 2A11

Expression System

Agrobacterium-mediated T-DNA

Host Strain

EHA105

Receptor Target

CaSR (calcium-sensing receptor)

IFI Score

487.5

Pathway Edits

  • CaSR positive cooperativity reengineering
  • Hill coefficient enhancement via dimer interface
  • Calcimimetic binding pocket expansion
  • ERK1/2 phosphorylation amplifier
  • RhoA-ROCK suppression edit
  • Cyclin-dependent kinase feedback removal
  • mTOR S6K branch attenuation

Key Interventions

positive cooperativity enhancementERK amplifier integration

IFI Subscale Profile

IFI Profile

IFI-S
—
IFI-U
—
IFI-B
—
IFI-K
487.5
IFI-C
—
IFI-P
—
IFI-A
—
IFI-F
—

Use Case

Processed cheese analog mouthfulness modulator

License

$149 · Tier III License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

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