IFI-K · CaSR Enhance
Specimen SS-F-KOK-095 // KOKUMI · IFI-K
CaSR Enhance II-IV-A
Capsicum annuum
Pepper
Tier IICaSR Enhance
Target Trait
2.63×
fold-change
CaSR receptor activation fold-change over wild-type
Technical Specifications
Genomic Edits
6
GC Content
49.1%
Construct Length
2,180 bp
Promoter System
T7/SP6 cell-free
Expression System
In-vitro cell-free
Host Strain
Cell-free
Receptor Target
CaSR (calcium-sensing receptor)
IFI Score
394.5
Pathway Edits
- CaSR biased agonism remodel toward Gαq
- GPCR kinase GRK2/3 expression reduction
- β-arrestin2 recruitment impairment
- Gαq11-PLCβ interface lock edit
- Diacylglycerol kinase silencing
- Protein kinase C translocation enhancer
Key Interventions
biased Gαq signaling lockGRK-mediated desensitization removal
IFI Subscale Profile
IFI Profile
IFI-S—
IFI-U—
IFI-B—
IFI-K394.5
IFI-C—
IFI-P—
IFI-A—
IFI-F—
Use Case
Spice blend kokumi amplifier ingredient
License
$99 · Tier II License
Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.
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