IFI-C · Cool Peak

Specimen SS-F-CLB-071 // COOL BURN · IFI-C

Cool Peak IV-IV-A

Capsicum annuum

Pepper

Tier IVCool Peak

Target Trait

1 ratio

TRPM8/TRPV1 ratio

TRPM8/TRPV1 activation ratio

Technical Specifications

Genomic Edits

8

GC Content

47.6%

Construct Length

3,360 bp

Promoter System

T7/SP6 cell-free

Expression System

In-vitro cell-free

Host Strain

Cell-free

Receptor Target

TRPM8 + TRPV1

IFI Score

400

Pathway Edits

  • TRPM8 coding sequence::codon-optimized insertion
  • L-menthol biosynthesis cluster (HMGR, MnS, PR) upregulation
  • Capsaicin pathway attenuation via CYP450 single-edit
  • Cooling compound transporter CcT1 upregulation

Key Interventions

TRPM8 channel peak-activity amplificationL-menthol biosynthesis flux rate enhancementSelective TRPV1 background tone retentionCooling-dominant dual-sensation flavor profile delivery

IFI Subscale Profile

IFI Profile

IFI-S
—
IFI-U
—
IFI-B
—
IFI-K
—
IFI-C
400
IFI-P
—
IFI-A
—
IFI-F
—

Use Case

Premium cooling-dominant food and beverage applications, sports nutrition products, breath-freshening formats, and functional cooling ingredient supply chains.

License

$249 · Tier IV License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

Already purchased?

Back to Cool Burn · IFI-CAll Modalities