PE-2 Y4-DUAL-PH

Saccharomyces cerevisiae

Yeast

PE-2 SeriesTier 4

Target Trait

200

mg/L

Reported target: 200 mg/L capsaicin

Technical Specifications

Genomic Edits

GC Content

(41%)

Construct Length

24,800 bp

Promoter System

TEF1/PGK1/GAL1/ADH1 constitutive array

Expression System

Yeast genomic integration (4 loci)

Host Strain

PE-2

Pathway Edits

ARO4(K229L) feedback-resistant
ARO7(G141S) feedback-resistant
ΔARO10
ΔPAD1
Pun1(S39L) variant — enhanced acyltransferase activity
ESM2 chaperone co-expression

Key Interventions

Pun1(S39L) point mutant increases acyltransferase kcatESM2 co-expression stabilizes Pun1 folding

Application Domains

PharmaceuticalResearch

Intended Use

High-yield Brazilian industrial strain achieving up to 200 mg/L capsaicin; optimized for pharmaceutical-grade capsaicin APIs and research applications. with Pun1(S39L) acyltransferase enhancement.

Access

Request Commercial Access

This construct is available exclusively to qualified institutions. Submit an inquiry to receive technical documentation and licensing terms.

No pricing is listed publicly. We respond to all qualified inquiries within 2 business days.

Back to Commercial Catalog