Specimen SS-COM-YST-0282 // YEAST
CEN.PK-A Y5-BASE-PH
Saccharomyces cerevisiae
Yeast
Target Trait
300
mg/L
Reported target: 300 mg/L capsaicin
Technical Specifications
Genomic Edits
9
GC Content
(41%)
Construct Length
20,500 bp
Promoter System
TEF1/PGK1/GAL1/ADH1 constitutive array
Expression System
Yeast genomic integration (4 loci)
Host Strain
CEN.PK-A
Pathway Edits
- ARO4(K229L) feedback-resistant
- ARO7(G141S) feedback-resistant
- ΔARO10 (phenylpyruvate decarboxylase knockout)
- ΔPAD1 (phenylacrylic acid decarboxylase knockout)
- pAMT genomic integration (TEF1 promoter)
- Pun1 integration (PGK1 promoter)
Key Interventions
Application Domains
Intended Use
Industrial food-grade chassis engineered for 300 mg/L capsaicin output; suited for pharmaceutical-grade capsaicin APIs and research applications..
Access
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