Specimen SS-COM-YST-0234 // YEAST
CEN.PK-A Y2-ARO+-PH
Saccharomyces cerevisiae
Yeast
Target Trait
100
mg/L
Reported target: 100 mg/L capsaicin
Technical Specifications
Genomic Edits
15
GC Content
(41%)
Construct Length
26,200 bp
Promoter System
TEF1/PGK1/GAL1/ADH1 constitutive array
Expression System
Yeast genomic integration (4 loci)
Host Strain
CEN.PK-A
Pathway Edits
- ARO4(K229L) feedback-resistant (2× copy number)
- ARO7(G141S) feedback-resistant (2× copy number)
- ΔARO10
- ΔPAD1
- Additional ARO4 copy at HO locus
- TKL1/TKL2 overexpression for E4P supply
Key Interventions
Application Domains
Intended Use
Industrial food-grade chassis engineered for 100 mg/L capsaicin output; suited for pharmaceutical-grade capsaicin APIs and research applications..
Access
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