Commercial Access Only

Specimen SS-COM-CLB-0995 // COOL-BURN

Arctic Burn T5-PR-GX

Capsicum annuum

Hungarian Wax

Arctic Burn SeriesTier 5

Target Trait

2.5

TRPM8/TRPV1 ratio

Reported target: TRPM8/TRPV1 ratio 2.5

Technical Specifications

Genomic Edits

13

GC Content

(57%)

Construct Length

11,260 bp

Promoter System

Ubiquitin / T7

Expression System

Protoplast PEG-fusion

Host Strain

PEG-mediated

Pathway Edits

  • TRPM8 Y745H gain-of-function
  • TRPV1 co-regulation
  • Full biphasic thermosensory axis
  • Menthol + Icilin co-production

Key Interventions

Arctic burn peak TRPM8 engineering with voltage-sensor domain stabilizationMaximum TRPM8/TRPV1 biphasic axis via full thermosensory rewiring

Application Domains

Food ManufacturingPharmaceuticalAgricultural BiotechIndustrialResearch

Intended Use

Multi-domain Arctic Burn T5 commercial construct; TRPM8/TRPV1 ratio 2.5. Full regulatory documentation package spanning food manufacturing, pharmaceutical, agricultural biotech, industrial, and research applications. Broadest deployment envelope in the Cool-Burn portfolio.

Access

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