Arctic Burn T4-PR-PH

Capsicum annuum

Hungarian Wax

Arctic Burn SeriesTier 4

Target Trait

2.33

TRPM8/TRPV1 ratio

Reported target: TRPM8/TRPV1 ratio 2.33

Technical Specifications

Genomic Edits

GC Content

(55%)

Construct Length

10,240 bp

Promoter System

Ubiquitin / T7

Expression System

Protoplast PEG-fusion

Host Strain

PEG-mediated

Pathway Edits

TRPM8 gain-of-function
TRPV1 co-expression tuning
Icilin analog synthesis

Key Interventions

Arctic burn peak TRPM8 engineering with voltage-sensor domain stabilizationMaximum TRPM8/TRPV1 biphasic axis via full thermosensory rewiring

Application Domains

PharmaceuticalResearch

Intended Use

Pharmaceutical-grade dual thermosensory construct; Arctic Burn T4 at TRPM8/TRPV1 ratio 2.33. Validated for topical analgesic formulation development, TRPM8/TRPV1 modulator pharmacology, thermosensory pain-relief delivery systems, and preclinical cold/heat receptor research.

Access

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