Commercial Access Only

Specimen SS-COM-CLB-0919 // COOL-BURN

Arctic Burn T1-IV-RS

Capsicum annuum

Hungarian Wax

Arctic Burn SeriesTier 1

Target Trait

1.8

TRPM8/TRPV1 ratio

Reported target: TRPM8/TRPV1 ratio 1.8

Technical Specifications

Genomic Edits

8

GC Content

(49%)

Construct Length

6,960 bp

Promoter System

T7/SP6 cell-free

Expression System

In-vitro cell-free

Host Strain

Cell-free

Pathway Edits

  • TRPM8 partial activation scaffold
  • TRPV1 baseline maintenance

Key Interventions

Arctic burn peak TRPM8 engineering with voltage-sensor domain stabilizationMaximum TRPM8/TRPV1 biphasic axis via full thermosensory rewiring

Application Domains

Research

Intended Use

Research-grade Arctic Burn T1 construct; TRPM8/TRPV1 ratio 1.8. Optimized for mechanistic studies of biphasic thermosensation, TRPM8/TRPV1 ion channel co-activation kinetics, dual-receptor pharmacology screening, and cool-burn sensation pathway dissection.

Access

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