Commercial Access Only

Specimen SS-COM-CLB-0900 // COOL-BURN

Menthol Bridge T5-IV-GX

Capsicum chinense

Bhut Jolokia

Menthol Bridge SeriesTier 5

Target Trait

2.3

TRPM8/TRPV1 ratio

Reported target: TRPM8/TRPV1 ratio 2.3

Technical Specifications

Genomic Edits

12

GC Content

(55%)

Construct Length

11,040 bp

Promoter System

T7/SP6 cell-free

Expression System

In-vitro cell-free

Host Strain

Cell-free

Pathway Edits

  • TRPM8 Y745H gain-of-function
  • TRPV1 co-regulation
  • Full biphasic thermosensory axis
  • Menthol + Icilin co-production

Key Interventions

Menthol and icilin co-production pathway via dual-module terpene synthaseTRPM8/TRPV1 ratio optimization scaffold with feedback-insensitive promoters

Application Domains

Food ManufacturingPharmaceuticalAgricultural BiotechIndustrialResearch

Intended Use

Multi-domain Menthol Bridge T5 commercial construct; TRPM8/TRPV1 ratio 2.3. Full regulatory documentation package spanning food manufacturing, pharmaceutical, agricultural biotech, industrial, and research applications. Broadest deployment envelope in the Cool-Burn portfolio.

Access

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