Menthol Bridge T1-IV-RS

Capsicum chinense

Bhut Jolokia

Menthol Bridge SeriesTier 1

Target Trait

1.6

TRPM8/TRPV1 ratio

Reported target: TRPM8/TRPV1 ratio 1.6

Technical Specifications

Genomic Edits

GC Content

(48%)

Construct Length

6,740 bp

Promoter System

T7/SP6 cell-free

Expression System

In-vitro cell-free

Host Strain

Cell-free

Pathway Edits

TRPM8 partial activation scaffold
TRPV1 baseline maintenance

Key Interventions

Menthol and icilin co-production pathway via dual-module terpene synthaseTRPM8/TRPV1 ratio optimization scaffold with feedback-insensitive promoters

Application Domains

Research

Intended Use

Research-grade Menthol Bridge T1 construct; TRPM8/TRPV1 ratio 1.6. Optimized for mechanistic studies of biphasic thermosensation, TRPM8/TRPV1 ion channel co-activation kinetics, dual-receptor pharmacology screening, and cool-burn sensation pathway dissection.

Access

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