Menthol Bridge T1-BL-PH

Capsicum chinense

Bhut Jolokia

Menthol Bridge SeriesTier 1

Target Trait

1.6

TRPM8/TRPV1 ratio

Reported target: TRPM8/TRPV1 ratio 1.6

Technical Specifications

Genomic Edits

GC Content

(48%)

Construct Length

6,740 bp

Promoter System

CaMV 35S / Ubiquitin

Expression System

Biolistic transformation

Host Strain

Particle Gun

Pathway Edits

TRPM8 partial activation scaffold
TRPV1 baseline maintenance

Key Interventions

Menthol and icilin co-production pathway via dual-module terpene synthaseTRPM8/TRPV1 ratio optimization scaffold with feedback-insensitive promoters

Application Domains

PharmaceuticalResearch

Intended Use

Pharmaceutical-grade dual thermosensory construct; Menthol Bridge T1 at TRPM8/TRPV1 ratio 1.6. Validated for topical analgesic formulation development, TRPM8/TRPV1 modulator pharmacology, thermosensory pain-relief delivery systems, and preclinical cold/heat receptor research.

Access

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