Commercial Access Only

Specimen SS-COM-CLB-0779 // COOL-BURN

Biphasic Grade T4-IV-RS

Capsicum annuum

Thai Bird

Biphasic Grade SeriesTier 4

Target Trait

1.93

TRPM8/TRPV1 ratio

Reported target: TRPM8/TRPV1 ratio 1.93

Technical Specifications

Genomic Edits

10

GC Content

(52%)

Construct Length

9,800 bp

Promoter System

T7/SP6 cell-free

Expression System

In-vitro cell-free

Host Strain

Cell-free

Pathway Edits

  • TRPM8 gain-of-function
  • TRPV1 co-expression tuning
  • Icilin analog synthesis

Key Interventions

Full biphasic thermosensory axis with tissue-specific temporal gatingTRPM8 + TRPV1 stoichiometric tuning via protein scaffold co-localization

Application Domains

Research

Intended Use

Research-grade Biphasic Grade T4 construct; TRPM8/TRPV1 ratio 1.93. Optimized for mechanistic studies of biphasic thermosensation, TRPM8/TRPV1 ion channel co-activation kinetics, dual-receptor pharmacology screening, and cool-burn sensation pathway dissection.

Access

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