Commercial Access Only

Specimen SS-COM-CLB-0739 // COOL-BURN

Biphasic Grade T2-IV-RS

Capsicum annuum

Thai Bird

Biphasic Grade SeriesTier 2

Target Trait

1.57

TRPM8/TRPV1 ratio

Reported target: TRPM8/TRPV1 ratio 1.57

Technical Specifications

Genomic Edits

7

GC Content

(48%)

Construct Length

7,540 bp

Promoter System

T7/SP6 cell-free

Expression System

In-vitro cell-free

Host Strain

Cell-free

Pathway Edits

  • TRPM8 channel upregulation
  • Menthol analog pathway induction

Key Interventions

Full biphasic thermosensory axis with tissue-specific temporal gatingTRPM8 + TRPV1 stoichiometric tuning via protein scaffold co-localization

Application Domains

Research

Intended Use

Research-grade Biphasic Grade T2 construct; TRPM8/TRPV1 ratio 1.57. Optimized for mechanistic studies of biphasic thermosensation, TRPM8/TRPV1 ion channel co-activation kinetics, dual-receptor pharmacology screening, and cool-burn sensation pathway dissection.

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