Commercial Access Only

Specimen SS-COM-CLB-0661 // COOL-BURN

Cooling Edge T4-AG-FD

Capsicum chinense

Carolina Reaper

Cooling Edge SeriesTier 4

Target Trait

1.8

TRPM8/TRPV1 ratio

Reported target: TRPM8/TRPV1 ratio 1.8

Technical Specifications

Genomic Edits

9

GC Content

(51%)

Construct Length

9,580 bp

Promoter System

Tissue-specific 2A11

Expression System

Agrobacterium-mediated T-DNA

Host Strain

EHA105

Pathway Edits

  • TRPM8 gain-of-function
  • TRPV1 co-expression tuning
  • Icilin analog synthesis

Key Interventions

TRPM8 Y745H gain-of-function variant with enhanced cold threshold shiftIcilin analog biosynthesis pathway via heterologous terpene enzymes

Application Domains

Food Manufacturing

Intended Use

Food-grade cool-burn formulation; Cooling Edge T4 at TRPM8/TRPV1 ratio 1.8. Suitable for novel cooling confectionery, thermosensory beverage ingredients, biphasic hot-cold flavor compounds, and dual-sensation spice blends for commercial food manufacturing.

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