Cooling Edge T2-AG-RS

Capsicum chinense

Carolina Reaper

Cooling Edge SeriesTier 2

Target Trait

1.4

TRPM8/TRPV1 ratio

Reported target: TRPM8/TRPV1 ratio 1.4

Technical Specifications

Genomic Edits

GC Content

(48%)

Construct Length

7,540 bp

Promoter System

Tissue-specific 2A11

Expression System

Agrobacterium-mediated T-DNA

Host Strain

EHA105

Pathway Edits

TRPM8 channel upregulation
Menthol analog pathway induction

Key Interventions

TRPM8 Y745H gain-of-function variant with enhanced cold threshold shiftIcilin analog biosynthesis pathway via heterologous terpene enzymes

Application Domains

Research

Intended Use

Research-grade Cooling Edge T2 construct; TRPM8/TRPV1 ratio 1.4. Optimized for mechanistic studies of biphasic thermosensation, TRPM8/TRPV1 ion channel co-activation kinetics, dual-receptor pharmacology screening, and cool-burn sensation pathway dissection.

Access

Request Commercial Access

This construct is available exclusively to qualified institutions. Submit an inquiry to receive technical documentation and licensing terms.

No pricing is listed publicly. We respond to all qualified inquiries within 2 business days.

Back to Commercial Catalog