Commercial Access Only

Specimen SS-COM-CLB-0517 // COOL-BURN

Ice-Fire Scale T1-IV-PH

Capsicum annuum

Serrano

Ice-Fire Scale SeriesTier 1

Target Trait

1

TRPM8/TRPV1 ratio

Reported target: TRPM8/TRPV1 ratio 1

Technical Specifications

Genomic Edits

5

GC Content

(45%)

Construct Length

6,300 bp

Promoter System

T7/SP6 cell-free

Expression System

In-vitro cell-free

Host Strain

Cell-free

Pathway Edits

  • TRPM8 partial activation scaffold
  • TRPV1 baseline maintenance

Key Interventions

TRPM8 constitutive gain-of-function via S1 helix engineeringTRPV1 co-regulated expression with convergent promoter architecture

Application Domains

PharmaceuticalResearch

Intended Use

Pharmaceutical-grade dual thermosensory construct; Ice-Fire Scale T1 at TRPM8/TRPV1 ratio 1. Validated for topical analgesic formulation development, TRPM8/TRPV1 modulator pharmacology, thermosensory pain-relief delivery systems, and preclinical cold/heat receptor research.

Access

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