Commercial Access Only

Specimen SS-COM-CLB-0487 // COOL-BURN

Thermal Contrast T5-BL-PH

Capsicum chinense

Ghost Pepper

Thermal Contrast SeriesTier 5

Target Trait

1.6

TRPM8/TRPV1 ratio

Reported target: TRPM8/TRPV1 ratio 1.6

Technical Specifications

Genomic Edits

9

GC Content

(51%)

Construct Length

10,380 bp

Promoter System

CaMV 35S / Ubiquitin

Expression System

Biolistic transformation

Host Strain

Particle Gun

Pathway Edits

  • TRPM8 Y745H gain-of-function
  • TRPV1 co-regulation
  • Full biphasic thermosensory axis
  • Menthol + Icilin co-production

Key Interventions

Biphasic thermal axis co-engineering (cold 8–28°C + heat 42°C+ gates)TRPM8/TRPV1 simultaneous co-activation scaffold with ratio stabilizer

Application Domains

PharmaceuticalResearch

Intended Use

Pharmaceutical-grade dual thermosensory construct; Thermal Contrast T5 at TRPM8/TRPV1 ratio 1.6. Validated for topical analgesic formulation development, TRPM8/TRPV1 modulator pharmacology, thermosensory pain-relief delivery systems, and preclinical cold/heat receptor research.

Access

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