Commercial Access Only

Specimen SS-COM-CLB-0422 // COOL-BURN

Thermal Contrast T2-AG-PH

Capsicum chinense

Ghost Pepper

Thermal Contrast SeriesTier 2

Target Trait

1

TRPM8/TRPV1 ratio

Reported target: TRPM8/TRPV1 ratio 1

Technical Specifications

Genomic Edits

6

GC Content

(46%)

Construct Length

7,320 bp

Promoter System

Tissue-specific 2A11

Expression System

Agrobacterium-mediated T-DNA

Host Strain

EHA105

Pathway Edits

  • TRPM8 channel upregulation
  • Menthol analog pathway induction

Key Interventions

Biphasic thermal axis co-engineering (cold 8–28°C + heat 42°C+ gates)TRPM8/TRPV1 simultaneous co-activation scaffold with ratio stabilizer

Application Domains

PharmaceuticalResearch

Intended Use

Pharmaceutical-grade dual thermosensory construct; Thermal Contrast T2 at TRPM8/TRPV1 ratio 1. Validated for topical analgesic formulation development, TRPM8/TRPV1 modulator pharmacology, thermosensory pain-relief delivery systems, and preclinical cold/heat receptor research.

Access

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