Commercial Access Only

Specimen SS-COM-CLB-0412 // COOL-BURN

Thermal Contrast T1-PR-PH

Capsicum chinense

Ghost Pepper

Thermal Contrast SeriesTier 1

Target Trait

0.8

TRPM8/TRPV1 ratio

Reported target: TRPM8/TRPV1 ratio 0.8

Technical Specifications

Genomic Edits

5

GC Content

(45%)

Construct Length

6,300 bp

Promoter System

Ubiquitin / T7

Expression System

Protoplast PEG-fusion

Host Strain

PEG-mediated

Pathway Edits

  • TRPM8 partial activation scaffold
  • TRPV1 baseline maintenance

Key Interventions

Biphasic thermal axis co-engineering (cold 8–28°C + heat 42°C+ gates)TRPM8/TRPV1 simultaneous co-activation scaffold with ratio stabilizer

Application Domains

PharmaceuticalResearch

Intended Use

Pharmaceutical-grade dual thermosensory construct; Thermal Contrast T1 at TRPM8/TRPV1 ratio 0.8. Validated for topical analgesic formulation development, TRPM8/TRPV1 modulator pharmacology, thermosensory pain-relief delivery systems, and preclinical cold/heat receptor research.

Access

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