Commercial Access Only

Specimen SS-COM-CLB-0404 // COOL-BURN

Thermal Contrast T1-AG-RS

Capsicum chinense

Ghost Pepper

Thermal Contrast SeriesTier 1

Target Trait

0.8

TRPM8/TRPV1 ratio

Reported target: TRPM8/TRPV1 ratio 0.8

Technical Specifications

Genomic Edits

5

GC Content

(45%)

Construct Length

6,300 bp

Promoter System

Tissue-specific 2A11

Expression System

Agrobacterium-mediated T-DNA

Host Strain

EHA105

Pathway Edits

  • TRPM8 partial activation scaffold
  • TRPV1 baseline maintenance

Key Interventions

Biphasic thermal axis co-engineering (cold 8–28°C + heat 42°C+ gates)TRPM8/TRPV1 simultaneous co-activation scaffold with ratio stabilizer

Application Domains

Research

Intended Use

Research-grade Thermal Contrast T1 construct; TRPM8/TRPV1 ratio 0.8. Optimized for mechanistic studies of biphasic thermosensation, TRPM8/TRPV1 ion channel co-activation kinetics, dual-receptor pharmacology screening, and cool-burn sensation pathway dissection.

Access

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