TRPM8 Tier T4-PR-FD

Capsicum annuum

Jalapeño

TRPM8 Tier SeriesTier 4

Target Trait

1.2

TRPM8/TRPV1 ratio

Reported target: TRPM8/TRPV1 ratio 1.2

Technical Specifications

Genomic Edits

GC Content

(48%)

Construct Length

9,140 bp

Promoter System

Ubiquitin / T7

Expression System

Protoplast PEG-fusion

Host Strain

PEG-mediated

Pathway Edits

TRPM8 gain-of-function
TRPV1 co-expression tuning
Icilin analog synthesis

Key Interventions

TRPM8 multi-copy overexpression via tandem promoter architectureTRPV1 concurrent expression scaffold with independent terminator

Application Domains

Food Manufacturing

Intended Use

Food-grade cool-burn formulation; TRPM8 Tier T4 at TRPM8/TRPV1 ratio 1.2. Suitable for novel cooling confectionery, thermosensory beverage ingredients, biphasic hot-cold flavor compounds, and dual-sensation spice blends for commercial food manufacturing.

Access

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