TRPM8 Tier T3-AG-RS

Capsicum annuum

Jalapeño

TRPM8 Tier SeriesTier 3

Target Trait

TRPM8/TRPV1 ratio

Reported target: TRPM8/TRPV1 ratio 1

Technical Specifications

Genomic Edits

GC Content

(46%)

Construct Length

8,120 bp

Promoter System

Tissue-specific 2A11

Expression System

Agrobacterium-mediated T-DNA

Host Strain

EHA105

Pathway Edits

TRPM8 constitutive activation
TRPV1 concurrent flux
Thermal contrast scaffold

Key Interventions

TRPM8 multi-copy overexpression via tandem promoter architectureTRPV1 concurrent expression scaffold with independent terminator

Application Domains

Research

Intended Use

Research-grade TRPM8 Tier T3 construct; TRPM8/TRPV1 ratio 1. Optimized for mechanistic studies of biphasic thermosensation, TRPM8/TRPV1 ion channel co-activation kinetics, dual-receptor pharmacology screening, and cool-burn sensation pathway dissection.

Access

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