Commercial Access Only

Specimen SS-COM-CLB-0290 // COOL-BURN

Menthol Analog T5-BL-GX

Capsicum chinense

Scotch Bonnet

Menthol Analog SeriesTier 5

Target Trait

1

TRPM8/TRPV1 ratio

Reported target: TRPM8/TRPV1 ratio 1

Technical Specifications

Genomic Edits

7

GC Content

(48%)

Construct Length

9,940 bp

Promoter System

CaMV 35S / Ubiquitin

Expression System

Biolistic transformation

Host Strain

Particle Gun

Pathway Edits

  • TRPM8 Y745H gain-of-function
  • TRPV1 co-regulation
  • Full biphasic thermosensory axis
  • Menthol + Icilin co-production

Key Interventions

Menthol-binding-site TRPM8 residue engineering (Y745/R842)Linalool and menthol analog biosynthesis via terpene pathway upregulation

Application Domains

Food ManufacturingPharmaceuticalAgricultural BiotechIndustrialResearch

Intended Use

Multi-domain Menthol Analog T5 commercial construct; TRPM8/TRPV1 ratio 1. Full regulatory documentation package spanning food manufacturing, pharmaceutical, agricultural biotech, industrial, and research applications. Broadest deployment envelope in the Cool-Burn portfolio.

Access

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