Menthol Analog T4-PR-GX

Capsicum chinense

Scotch Bonnet

Menthol Analog SeriesTier 4

Target Trait

0.85

TRPM8/TRPV1 ratio

Reported target: TRPM8/TRPV1 ratio 0.85

Technical Specifications

Genomic Edits

GC Content

(46%)

Construct Length

8,920 bp

Promoter System

Ubiquitin / T7

Expression System

Protoplast PEG-fusion

Host Strain

PEG-mediated

Pathway Edits

TRPM8 gain-of-function
TRPV1 co-expression tuning
Icilin analog synthesis

Key Interventions

Menthol-binding-site TRPM8 residue engineering (Y745/R842)Linalool and menthol analog biosynthesis via terpene pathway upregulation

Application Domains

Food ManufacturingPharmaceuticalAgricultural BiotechIndustrialResearch

Intended Use

Multi-domain Menthol Analog T4 commercial construct; TRPM8/TRPV1 ratio 0.85. Full regulatory documentation package spanning food manufacturing, pharmaceutical, agricultural biotech, industrial, and research applications. Broadest deployment envelope in the Cool-Burn portfolio.

Access

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