Commercial Access Only

Specimen SS-COM-CLB-0272 // COOL-BURN

Menthol Analog T4-PR-PH

Capsicum chinense

Scotch Bonnet

Menthol Analog SeriesTier 4

Target Trait

0.85

TRPM8/TRPV1 ratio

Reported target: TRPM8/TRPV1 ratio 0.85

Technical Specifications

Genomic Edits

6

GC Content

(46%)

Construct Length

8,920 bp

Promoter System

Ubiquitin / T7

Expression System

Protoplast PEG-fusion

Host Strain

PEG-mediated

Pathway Edits

  • TRPM8 gain-of-function
  • TRPV1 co-expression tuning
  • Icilin analog synthesis

Key Interventions

Menthol-binding-site TRPM8 residue engineering (Y745/R842)Linalool and menthol analog biosynthesis via terpene pathway upregulation

Application Domains

PharmaceuticalResearch

Intended Use

Pharmaceutical-grade dual thermosensory construct; Menthol Analog T4 at TRPM8/TRPV1 ratio 0.85. Validated for topical analgesic formulation development, TRPM8/TRPV1 modulator pharmacology, thermosensory pain-relief delivery systems, and preclinical cold/heat receptor research.

Access

Request Commercial Access

This construct is available exclusively to qualified institutions. Submit an inquiry to receive technical documentation and licensing terms.

Contact Us →

No pricing is listed publicly. We respond to all qualified inquiries within 2 business days.

Back to Commercial Catalog