Commercial Access Only

Specimen SS-COM-CLB-0271 // COOL-BURN

Menthol Analog T4-PR-FD

Capsicum chinense

Scotch Bonnet

Menthol Analog SeriesTier 4

Target Trait

0.85

TRPM8/TRPV1 ratio

Reported target: TRPM8/TRPV1 ratio 0.85

Technical Specifications

Genomic Edits

6

GC Content

(46%)

Construct Length

8,920 bp

Promoter System

Ubiquitin / T7

Expression System

Protoplast PEG-fusion

Host Strain

PEG-mediated

Pathway Edits

  • TRPM8 gain-of-function
  • TRPV1 co-expression tuning
  • Icilin analog synthesis

Key Interventions

Menthol-binding-site TRPM8 residue engineering (Y745/R842)Linalool and menthol analog biosynthesis via terpene pathway upregulation

Application Domains

Food Manufacturing

Intended Use

Food-grade cool-burn formulation; Menthol Analog T4 at TRPM8/TRPV1 ratio 0.85. Suitable for novel cooling confectionery, thermosensory beverage ingredients, biphasic hot-cold flavor compounds, and dual-sensation spice blends for commercial food manufacturing.

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