Commercial Access Only

Specimen SS-COM-CLB-0247 // COOL-BURN

Menthol Analog T3-BL-PH

Capsicum chinense

Scotch Bonnet

Menthol Analog SeriesTier 3

Target Trait

0.7

TRPM8/TRPV1 ratio

Reported target: TRPM8/TRPV1 ratio 0.7

Technical Specifications

Genomic Edits

5

GC Content

(45%)

Construct Length

7,900 bp

Promoter System

CaMV 35S / Ubiquitin

Expression System

Biolistic transformation

Host Strain

Particle Gun

Pathway Edits

  • TRPM8 constitutive activation
  • TRPV1 concurrent flux
  • Thermal contrast scaffold

Key Interventions

Menthol-binding-site TRPM8 residue engineering (Y745/R842)Linalool and menthol analog biosynthesis via terpene pathway upregulation

Application Domains

PharmaceuticalResearch

Intended Use

Pharmaceutical-grade dual thermosensory construct; Menthol Analog T3 at TRPM8/TRPV1 ratio 0.7. Validated for topical analgesic formulation development, TRPM8/TRPV1 modulator pharmacology, thermosensory pain-relief delivery systems, and preclinical cold/heat receptor research.

Access

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