Commercial Access Only

Specimen SS-COM-CLB-0236 // COOL-BURN

Menthol Analog T2-IV-FD

Capsicum chinense

Scotch Bonnet

Menthol Analog SeriesTier 2

Target Trait

0.55

TRPM8/TRPV1 ratio

Reported target: TRPM8/TRPV1 ratio 0.55

Technical Specifications

Genomic Edits

4

GC Content

(43%)

Construct Length

6,880 bp

Promoter System

T7/SP6 cell-free

Expression System

In-vitro cell-free

Host Strain

Cell-free

Pathway Edits

  • TRPM8 channel upregulation
  • Menthol analog pathway induction

Key Interventions

Menthol-binding-site TRPM8 residue engineering (Y745/R842)Linalool and menthol analog biosynthesis via terpene pathway upregulation

Application Domains

Food Manufacturing

Intended Use

Food-grade cool-burn formulation; Menthol Analog T2 at TRPM8/TRPV1 ratio 0.55. Suitable for novel cooling confectionery, thermosensory beverage ingredients, biphasic hot-cold flavor compounds, and dual-sensation spice blends for commercial food manufacturing.

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