Menthol Analog T1-PR-RS

Capsicum chinense

Scotch Bonnet

Menthol Analog SeriesTier 1

Target Trait

0.4

TRPM8/TRPV1 ratio

Reported target: TRPM8/TRPV1 ratio 0.4

Technical Specifications

Genomic Edits

GC Content

(42%)

Construct Length

5,860 bp

Promoter System

Ubiquitin / T7

Expression System

Protoplast PEG-fusion

Host Strain

PEG-mediated

Pathway Edits

TRPM8 partial activation scaffold
TRPV1 baseline maintenance

Key Interventions

Menthol-binding-site TRPM8 residue engineering (Y745/R842)Linalool and menthol analog biosynthesis via terpene pathway upregulation

Application Domains

Research

Intended Use

Research-grade Menthol Analog T1 construct; TRPM8/TRPV1 ratio 0.4. Optimized for mechanistic studies of biphasic thermosensation, TRPM8/TRPV1 ion channel co-activation kinetics, dual-receptor pharmacology screening, and cool-burn sensation pathway dissection.

Access

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