Cool Peak T4-PR-PH

Capsicum annuum

Cayenne

Cool Peak SeriesTier 4

Target Trait

0.95

TRPM8/TRPV1 ratio

Reported target: TRPM8/TRPV1 ratio 0.95

Technical Specifications

Genomic Edits

GC Content

(46%)

Construct Length

8,920 bp

Promoter System

Ubiquitin / T7

Expression System

Protoplast PEG-fusion

Host Strain

PEG-mediated

Pathway Edits

TRPM8 gain-of-function
TRPV1 co-expression tuning
Icilin analog synthesis

Key Interventions

Ubiquitin::TRPM8-high-expression dual-promoter cassetteTRPV1 channel stabilization via auxiliary subunit co-expression

Application Domains

PharmaceuticalResearch

Intended Use

Pharmaceutical-grade dual thermosensory construct; Cool Peak T4 at TRPM8/TRPV1 ratio 0.95. Validated for topical analgesic formulation development, TRPM8/TRPV1 modulator pharmacology, thermosensory pain-relief delivery systems, and preclinical cold/heat receptor research.

Access

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