Cool Peak T1-IV-RS

Capsicum annuum

Cayenne

Cool Peak SeriesTier 1

Target Trait

0.5

TRPM8/TRPV1 ratio

Reported target: TRPM8/TRPV1 ratio 0.5

Technical Specifications

Genomic Edits

GC Content

(43%)

Construct Length

6,080 bp

Promoter System

T7/SP6 cell-free

Expression System

In-vitro cell-free

Host Strain

Cell-free

Pathway Edits

TRPM8 partial activation scaffold
TRPV1 baseline maintenance

Key Interventions

Ubiquitin::TRPM8-high-expression dual-promoter cassetteTRPV1 channel stabilization via auxiliary subunit co-expression

Application Domains

Research

Intended Use

Research-grade Cool Peak T1 construct; TRPM8/TRPV1 ratio 0.5. Optimized for mechanistic studies of biphasic thermosensation, TRPM8/TRPV1 ion channel co-activation kinetics, dual-receptor pharmacology screening, and cool-burn sensation pathway dissection.

Access

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