Commercial Access Only

Specimen SS-COM-CLB-0097 // COOL-BURN

Dual Sensation T5-IV-PH

Capsicum chinense

Habanero

Dual Sensation SeriesTier 5

Target Trait

0.8

TRPM8/TRPV1 ratio

Reported target: TRPM8/TRPV1 ratio 0.8

Technical Specifications

Genomic Edits

6

GC Content

(46%)

Construct Length

9,720 bp

Promoter System

T7/SP6 cell-free

Expression System

In-vitro cell-free

Host Strain

Cell-free

Pathway Edits

  • TRPM8 Y745H gain-of-function
  • TRPV1 co-regulation
  • Full biphasic thermosensory axis
  • Menthol + Icilin co-production

Key Interventions

CaMV 35S::TRPM8-optimized codon expression cassetteCapsaicin pathway baseline maintenance via PAL1 stabilization

Application Domains

PharmaceuticalResearch

Intended Use

Pharmaceutical-grade dual thermosensory construct; Dual Sensation T5 at TRPM8/TRPV1 ratio 0.8. Validated for topical analgesic formulation development, TRPM8/TRPV1 modulator pharmacology, thermosensory pain-relief delivery systems, and preclinical cold/heat receptor research.

Access

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