Science

Culinary Genomics

Culinary genomics is the application of genomic tools — sequencing, CRISPR editing, metabolic modeling, and protein engineering — to the design and production of food flavors. It goes beyond conventional plant breeding or flavor chemistry by working directly at the level of the genes that encode flavor-producing enzymes.

What's Different

Conventional flavor engineering (plant breeding, extracts, synthetic flavor chemicals) works by selecting or combining what already exists in nature. Culinary genomics builds what doesn't exist: a pepper-heat gene pathway expressed in basil, a kokumi-enhancing glutamyl peptide cassette in soybeans, or a bitterness-free brassica. The design space is bounded only by biochemistry, not by what has evolved.

The Scoville Splice Approach

Scoville Splice's platform starts with fully sequenced pepper and crop genomes, runs enzyme variants through ESM2 for functional scoring, models metabolic feasibility with FBA, and validates constructs against the eight-axis Iyengar Flavor Index. The result is a catalog of 18,500+ engineered constructs that can be ordered, licensed, and introduced into target host plants.

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