Specimen SS-F-UMA-672 // UMAMI · IFI-U
Betaine mGluR1 IV-IV-B
Solanum lycopersicum
Tomato
Target Trait
2.45×
fold-change
Glycine betaine mGluR1 activity modulation index
Technical Specifications
SKU
SS-F-UMA-672
Genomic Edits
6
GC Content
46.2-52.2%
Construct Length
3,628 bp
Promoter System
T7/SP6 cell-free
Expression System
Cell-free T7/SP6 in-vitro
Host Strain
Cell-free
Receptor Target
mGluR1 / TAS1R1-TAS1R3
IFI Score
245
Pathway Edits
- SlBADH betaine aldehyde dehydrogenase overexpression under CaMV35S for glycine betaine accumulation from betaine aldehyde oxidation in tomato leaf and fruit tissue
- SlCMOB choline monooxygenase B upregulation for enhanced choline-to-betaine aldehyde oxidation, amplifying betaine synthesis flux
- SlBCSA betaine biosynthesis regulatory gene A overexpression for transcriptional activation of full betaine synthesis pathway
- SlCMO choline monooxygenase ancestral isoform introduction from Spinacia oleracea for expanded substrate-binding capacity
- SlCHOX choline oxidase heterologous expression from Arthrobacter globiformis for two-step choline-to-betaine direct oxidation pathway
- SlVTP vacuolar tonoplast protein upregulation for betaine compartmentalization and osmotic stress relief freeing cellular energy for flavor metabolism
Key Interventions
IFI Subscale Profile
IFI Profile
Use Case
Tomato products requiring umami roundness enhancement via betaine co-accumulation alongside free glutamate. Applicable to premium fresh-market tomatoes and functional food ingredients.
License
$4049 · Tier IV License
Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.
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