Propyl Disulfide Series I-PR-A

Allium sativum

Garlic

Tier IPropyl Disulfide Series

Target Trait

1.3×

fold-change

Dipropyl disulfide TRPA1 agonist fold-change

Technical Specifications

SKU

SS-F-TRP-445

Genomic Edits

GC Content

48.5%

Construct Length

2,536 bp

Promoter System

Ubiquitin / T7

Expression System

Protoplast PEG-fusion

Host Strain

PEG-mediated

Receptor Target

TRPA1

IFI Score

130

Pathway Edits

C-S lyase (cysteine-sulfoxide lyase) upregulation for propyl-cysteine sulfoxide cleavage and DPS precursor liberation
Propylcysteine sulfoxide (PCSO) biosynthesis pathway amplification via propyl-substituted cysteine S-oxidase
FMO3 (flavin-dependent monooxygenase 3) upregulation for S-oxidation of S-propyl-L-cysteine to propyl sulfoxide form

Key Interventions

C-S lyase/PCSO pathway amplification for dipropyl disulfide (DPS) TRPA1 agonist accumulation in Allium sativum platformFMO3-driven propyl-cysteine S-oxidation maximizes PCSO precursor pool for C-S lyase substrate availabilityDPS TRPA1 activation confirmed by calcium-flux assay; dipropyl disulfide engages TRPA1 electrophilic binding site with characteristic onion-sulfur pungency profilePEG-mediated transient expression protocol validated for rapid phenotypic pathway screening

IFI Subscale Profile

IFI Profile

IFI-S

—

IFI-U

—

IFI-B

—

IFI-K

—

IFI-C

—

IFI-P

130

IFI-A

—

IFI-F

—

Use Case

Tier I DPS-enriched Allium ingredient for cooked-onion and mild garlic flavor profiles in processed foods, TRPA1-selective sulfurous pungency in soups, stews, and savory condiments requiring a less pungent but warm, penetrating sulfur character. Suitable for applications where allicin's sharp raw-garlic volatility is undesirable but TRPA1-mediated warmth and sulfurous depth are targeted flavor attributes.

License

$299 · Tier I License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

Already purchased?

Back to Pungent · IFI-P All Modalities