IFI-S · TAS1R2/R3 Allosteric Enhancement Series

Specimen SS-F-SWT-969 // SWEET · IFI-S

TAS1R2/R3 Allosteric Enhancement Series II-AG-A

Solanum lycopersicum

Tomato

Tier IITAS1R2/R3 Allosteric Enhancement Series

Target Trait

2.13×

fold-change

TAS1R2/R3 response fold-change

Technical Specifications

SKU

SS-F-SWT-969

Genomic Edits

5

GC Content

47.8%

Construct Length

3,235 bp

Promoter System

35S CaMV promoter

Expression System

Agrobacterium-mediated T-DNA

Host Strain

EHA105

Receptor Target

TAS1R2/TAS1R3

IFI Score

213

Pathway Edits

  • OBP1 odorant binding protein-like overexpression for endogenous TAS1R allosteric modulator production
  • SW-TF sweetness-associated transcription factor overexpression for receptor density amplification
  • SEP1 signal enhancement protein 1 integration for downstream TAS1R2/TAS1R3 signaling amplification
  • TAS1R-modulator small molecule accumulation cassette for endogenous receptor potentiator synthesis
  • Gustducin alpha subunit co-expression for enhanced G-protein coupling efficiency in tomato

Key Interventions

OBP1 and TAS1R-modulator co-expression for endogenous allosteric receptor potentiator accumulationSW-TF sweetness transcription factor overexpression for TAS1R2/TAS1R3 receptor density enhancementSEP1 integration for amplified downstream TAS1R2/TAS1R3 signaling cascade response in tomato

IFI Subscale Profile

IFI Profile

IFI-S
213
IFI-U
—
IFI-B
—
IFI-K
—
IFI-C
—
IFI-P
—
IFI-A
—
IFI-F
—

Use Case

pilot-scale receptor sensitivity amplification for naturally enhanced sweet perception in tomato fruit

License

$699 · Tier II License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

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