Specimen SS-F-SWT-622 // SWEET · IFI-S
Sorbitol-to-Sweetness Series III-PR-B
Saccharum officinarum
Sugarcane
Target Trait
2.25×
fold-change
Sorbitol accumulation fold-change
Technical Specifications
SKU
SS-F-SWT-622
Genomic Edits
5
GC Content
43.8%
Construct Length
3,167 bp
Promoter System
35S CaMV promoter
Expression System
PEG-mediated protoplast transfection
Host Strain
PEG/calcium transfection
Receptor Target
TAS1R2/TAS1R3
IFI Score
225
Pathway Edits
- S6PDH sorbitol-6-phosphate dehydrogenase overexpression for direct conversion of glucose-6-P to sorbitol
- SDH sorbitol dehydrogenase downregulation to prevent catabolism of accumulated sorbitol
- SPS sucrose phosphate synthase activity optimization for sucrose-sorbitol metabolic balance
- SPP sucrose phosphate phosphatase co-expression for enhanced sucrose-to-sorbitol flux management
- Fructokinase activity suppression to redirect fructose toward the sorbitol biosynthetic route
- Vacuolar H+-ATPase upregulation for enhanced sorbitol compartmentalization in sugarcane
Key Interventions
IFI Subscale Profile
IFI Profile
Use Case
Enhanced performance variant: commercial sorbitol-enriched sugarcane platform for confectionery and pharmaceutical sweetener supply with amplified TAS1R2/TAS1R3 receptor activation for premium-tier applications
License
$1549 · Tier III License
Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.
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