CUK Tri-Axis Dominant-Primary Series II-NP

Mentha × piperita

Peppermint

Tier IICUK Tri-Axis Dominant-Primary Series

Target Trait

1.52×

fold-change

Cooling-dominant tri-axis U+K modulated fold-change

Technical Specifications

SKU

SS-F-M3-01985

Genomic Edits

GC Content

46.7%

Construct Length

5,129 bp

Promoter System

Lipid nanoparticle / Ubiquitin

Expression System

Nanoparticle delivery

Host Strain

LNP-mediated

Receptor Target

TRPM8 + mGluR1 + CaSR

IFI Score

152

Pathway Edits

TRPM8 pathway primary gene cluster for cooling (IFI-C) tri-axis component
mGluR1 pathway primary gene cluster for umami (IFI-U) tri-axis component
CaSR pathway primary gene cluster for kokumi (IFI-K) tri-axis component
Tri-axis metabolic flux partitioning hub for concurrent CUK pathway operation
Cross-pathway regulatory circuit for cooling-dominant CUK triple-axis expression
Cofactor regeneration system (NADPH, ATP, acetyl-CoA) supporting triple-axis concurrent production

Key Interventions

Triple-axis receptor co-activation: TRPM8, mGluR1, and CaSR pathways simultaneously engineeredCooling-dominant tri-axis expression strategy (CUK) with cross-pathway flux managementLNP-mediated delivery of triple-axis mRNA panel for transient expression profiling

IFI Subscale Profile

IFI Profile

IFI-S

—

IFI-U

—

IFI-B

—

IFI-K

—

IFI-C

—

IFI-P

—

IFI-A

—

IFI-F

—

Use Case

Tier II CUK triple-axis construct for advanced multi-modal sensory architecture combining cooling, umami, and kokumi axes. Suitable for ultra-premium ingredient formulation requiring certification across three simultaneous IFI receptor pathways.

License

$949 · Tier II License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

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