CUS Tri-Axis Balanced Series III-NP

Mentha × piperita

Peppermint

Tier IIICUS Tri-Axis Balanced Series

Target Trait

1.75×

fold-change

Cooling+Umami+Sweet balanced tri-axis fold-change

Technical Specifications

SKU

SS-F-M3-01865

Genomic Edits

GC Content

46.7%

Construct Length

5,366 bp

Promoter System

Lipid nanoparticle / Ubiquitin

Expression System

Nanoparticle delivery

Host Strain

LNP-mediated

Receptor Target

TRPM8 + mGluR1 + TAS1R2/TAS1R3

IFI Score

175

Pathway Edits

TRPM8 pathway primary gene cluster for cooling (IFI-C) tri-axis component
mGluR1 pathway primary gene cluster for umami (IFI-U) tri-axis component
TAS1R2/TAS1R3 pathway primary gene cluster for sweet (IFI-S) tri-axis component
Tri-axis metabolic flux partitioning hub for concurrent CUS pathway operation
Cross-pathway regulatory circuit for balanced CUS triple-axis expression
Cofactor regeneration system (NADPH, ATP, acetyl-CoA) supporting triple-axis concurrent production

Key Interventions

Triple-axis receptor co-activation: TRPM8, mGluR1, and TAS1R2/TAS1R3 pathways simultaneously engineeredBalanced tri-axis expression strategy (CUS) with cross-pathway flux managementLNP-mediated delivery of triple-axis mRNA panel for transient expression profiling

IFI Subscale Profile

IFI Profile

IFI-S

—

IFI-U

—

IFI-B

—

IFI-K

—

IFI-C

—

IFI-P

—

IFI-A

—

IFI-F

—

Use Case

Tier III CUS triple-axis construct for advanced multi-modal sensory architecture combining cooling, umami, and sweet axes. Suitable for ultra-premium ingredient formulation requiring certification across three simultaneous IFI receptor pathways.

License

$1749 · Tier III License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

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