UA Tissue-Specific Series II-AG-A

Solanum lycopersicum

Tomato

Tier IIUA Tissue-Specific Series

Target Trait

1.52×

fold-change

Umami+Astringency tissue-specific dual expression

Technical Specifications

SKU

SS-F-M2-05593

Genomic Edits

GC Content

47.5%

Construct Length

3,243 bp

Promoter System

Tissue-specific 2A11

Expression System

Agrobacterium-mediated T-DNA

Host Strain

EHA105

Receptor Target

mGluR1 + Polyphenol-astringency axis

IFI Score

152

Pathway Edits

mGluR1 pathway primary gene cluster overexpression for umami axis activation
Polyphenol-astringency axis pathway primary gene cluster overexpression for astringency axis activation
Bidirectional promoter system for synchronized U+A dual-axis co-expression
Metabolic flux partitioning between IFI-U and IFI-A pathway branches via carbon flow optimization
Transcription factor co-binding site engineering for Umami-Astringency combinatorial gene regulation

Key Interventions

Dual-receptor co-activation via synchronized mGluR1 and Polyphenol-astringency axis pathway engineeringMetabolic flux partitioning strategy enabling simultaneous umami and astringency accumulation without competing pathway suppressionTissue-specific dual expression for UA multi-axis integrationT-DNA binary vector 2A11 for stable genomic integration of multi-axis construct stack

IFI Subscale Profile

IFI Profile

IFI-S

—

IFI-U

—

IFI-B

—

IFI-K

—

IFI-C

—

IFI-P

—

IFI-A

—

IFI-F

—

Use Case

Tier II UA dual-axis tissue-specific platform for food ingredient applications requiring verified combined umami+astringency sensory character. Suitable for multi-modal flavor architecture, premium ingredient certification, and receptor-confirmed IFI multi-axis profiling.

License

$699 · Tier II License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

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