IFI-M · CS Tissue-Specific Series

Specimen SS-F-M2-04727 // MULTI-AXIS · IFI-M

CS Tissue-Specific Series IV-IV-B

Mentha × piperita

Peppermint

Tier IVCS Tissue-Specific Series

Target Trait

2.67×

fold-change

Cooling+Sweet tissue-specific dual expression

Technical Specifications

SKU

SS-F-M2-04727

Genomic Edits

9

GC Content

46%

Construct Length

4,703 bp

Promoter System

T7/SP6 cell-free

Expression System

In-vitro cell-free

Host Strain

Cell-free

Receptor Target

TRPM8 + TAS1R2/TAS1R3

IFI Score

267

Pathway Edits

  • TRPM8 pathway primary gene cluster overexpression for cooling axis activation
  • TAS1R2/TAS1R3 pathway primary gene cluster overexpression for sweet axis activation
  • Bidirectional promoter system for synchronized C+S dual-axis co-expression
  • Metabolic flux partitioning between IFI-C and IFI-S pathway branches via carbon flow optimization
  • Transcription factor co-binding site engineering for Cooling-Sweet combinatorial gene regulation
  • Cross-pathway feedback inhibition circuit removal for C+S simultaneous accumulation
  • Tissue-specific expression cassette deployment for optimized CS spatial patterning
  • Protein scaffold engineering for C+S enzyme co-localization

Key Interventions

Dual-receptor co-activation via synchronized TRPM8 and TAS1R2/TAS1R3 pathway engineeringMetabolic flux partitioning strategy enabling simultaneous cooling and sweet accumulation without competing pathway suppressionTissue-specific dual expression for CS multi-axis integrationCell-free co-translation of multi-axis enzyme sets for in-vitro biochemical validation

IFI Subscale Profile

IFI Profile

IFI-S
—
IFI-U
—
IFI-B
—
IFI-K
—
IFI-C
—
IFI-P
—
IFI-A
—
IFI-F
—

Use Case

Tier IV CS dual-axis tissue-specific platform for food ingredient applications requiring verified combined cooling+sweet sensory character. Suitable for multi-modal flavor architecture, premium ingredient certification, and receptor-confirmed IFI multi-axis profiling.

License

$4049 · Tier IV License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

Already purchased?

Back to Multi-Axis · IFI-MAll Modalities