CS Co-Expression Series II-BL-B

Mentha × piperita

Peppermint

Tier IICS Co-Expression Series

Target Trait

1.85×

fold-change

Cooling+Sweet co-activation fold-change

Technical Specifications

SKU

SS-F-M2-04517

Genomic Edits

GC Content

46.9%

Construct Length

3,531 bp

Promoter System

CaMV 35S / Ubiquitin

Expression System

Biolistic transformation

Host Strain

Particle Gun

Receptor Target

TRPM8 + TAS1R2/TAS1R3

IFI Score

185

Pathway Edits

TRPM8 pathway primary gene cluster overexpression for cooling axis activation
TAS1R2/TAS1R3 pathway primary gene cluster overexpression for sweet axis activation
Bidirectional promoter system for synchronized C+S dual-axis co-expression
Metabolic flux partitioning between IFI-C and IFI-S pathway branches via carbon flow optimization
Transcription factor co-binding site engineering for Cooling-Sweet combinatorial gene regulation
Cross-pathway feedback inhibition circuit removal for C+S simultaneous accumulation

Key Interventions

Dual-receptor co-activation via synchronized TRPM8 and TAS1R2/TAS1R3 pathway engineeringMetabolic flux partitioning strategy enabling simultaneous cooling and sweet accumulation without competing pathway suppressionCo-expression vector design for CS multi-axis integrationBiolistic co-bombardment of multi-axis transgene cassettes for high-copy integration events

IFI Subscale Profile

IFI Profile

IFI-S

—

IFI-U

—

IFI-B

—

IFI-K

—

IFI-C

—

IFI-P

—

IFI-A

—

IFI-F

—

Use Case

Tier II CS dual-axis co-expression platform for food ingredient applications requiring verified combined cooling+sweet sensory character. Suitable for multi-modal flavor architecture, premium ingredient certification, and receptor-confirmed IFI multi-axis profiling.

License

$749 · Tier II License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

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