CU Tissue-Specific Series II-AG-B

Mentha × piperita

Peppermint

Tier IICU Tissue-Specific Series

Target Trait

1.7×

fold-change

Cooling+Umami tissue-specific dual expression

Technical Specifications

SKU

SS-F-M2-04094

Genomic Edits

GC Content

45.4%

Construct Length

3,540 bp

Promoter System

Tissue-specific 2A11

Expression System

Agrobacterium-mediated T-DNA

Host Strain

EHA105

Receptor Target

TRPM8 + mGluR1

IFI Score

170

Pathway Edits

TRPM8 pathway primary gene cluster overexpression for cooling axis activation
mGluR1 pathway primary gene cluster overexpression for umami axis activation
Bidirectional promoter system for synchronized C+U dual-axis co-expression
Metabolic flux partitioning between IFI-C and IFI-U pathway branches via carbon flow optimization
Transcription factor co-binding site engineering for Cooling-Umami combinatorial gene regulation
Cross-pathway feedback inhibition circuit removal for C+U simultaneous accumulation

Key Interventions

Dual-receptor co-activation via synchronized TRPM8 and mGluR1 pathway engineeringMetabolic flux partitioning strategy enabling simultaneous cooling and umami accumulation without competing pathway suppressionTissue-specific dual expression for CU multi-axis integrationT-DNA binary vector 2A11 for stable genomic integration of multi-axis construct stack

IFI Subscale Profile

IFI Profile

IFI-S

—

IFI-U

—

IFI-B

—

IFI-K

—

IFI-C

—

IFI-P

—

IFI-A

—

IFI-F

—

Use Case

Tier II CU dual-axis tissue-specific platform for food ingredient applications requiring verified combined cooling+umami sensory character. Suitable for multi-modal flavor architecture, premium ingredient certification, and receptor-confirmed IFI multi-axis profiling.

License

$749 · Tier II License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

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