IFI-M · HC Tissue-Specific Series

Specimen SS-F-M2-00501 // MULTI-AXIS · IFI-M

HC Tissue-Specific Series II-PR-C

Capsicum chinense

Habanero

Tier IIHC Tissue-Specific Series

Target Trait

1.9×

fold-change

Heat+Cooling tissue-specific dual expression

Technical Specifications

SKU

SS-F-M2-00501

Genomic Edits

7

GC Content

47.6%

Construct Length

4,039 bp

Promoter System

Ubiquitin / T7

Expression System

Protoplast PEG-fusion

Host Strain

PEG-mediated

Receptor Target

TRPV1 + TRPM8

IFI Score

190

Pathway Edits

  • TRPV1 pathway primary gene cluster overexpression for heat axis activation
  • TRPM8 pathway primary gene cluster overexpression for cooling axis activation
  • Bidirectional promoter system for synchronized H+C dual-axis co-expression
  • Metabolic flux partitioning between IFI-H and IFI-C pathway branches via carbon flow optimization
  • Transcription factor co-binding site engineering for Heat-Cooling combinatorial gene regulation
  • Cross-pathway feedback inhibition circuit removal for H+C simultaneous accumulation
  • Tissue-specific expression cassette deployment for optimized HC spatial patterning

Key Interventions

Dual-receptor co-activation via synchronized TRPV1 and TRPM8 pathway engineeringMetabolic flux partitioning strategy enabling simultaneous heat and cooling accumulation without competing pathway suppressionTissue-specific dual expression for HC multi-axis integrationPEG-mediated co-transfection of axis constructs for rapid phenotypic screening of multi-axis combinations

IFI Subscale Profile

IFI Profile

IFI-S
—
IFI-U
—
IFI-B
—
IFI-K
—
IFI-C
—
IFI-P
—
IFI-A
—
IFI-F
—

Use Case

Tier II HC dual-axis tissue-specific platform for food ingredient applications requiring verified combined heat+cooling sensory character. Suitable for multi-modal flavor architecture, premium ingredient certification, and receptor-confirmed IFI multi-axis profiling.

License

$849 · Tier II License

Includes full construct sequence, CRISPR guide designs, pathway edit specifications, flux balance analysis, and IFI validation data.

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